Abstract
Coronary artery disease (CAD) is a leading cause of cardiovascular disease-related mortality globally. Traditional risk indicators for CAD, such as age, gender, hypertension, and cholesterol levels, may not reliably predict the existence and severity of the disease in all individuals. Furthermore, these risk variables may not provide information regarding the long-term prognosis and survival of the patients with stable CAD. The limitations of present screening approaches suggest the need to develop novel prognostic biomarkers for the detection of coronary atherosclerosis (CA). This review focuses on the significance of adipokines in the pathophysiology of CA. The article discusses the role of various cytokines, focusing on visfatin in developing and progressing coronary atheroma and its potential to improve risk stratification, increase diagnostic accuracy, and guide therapy decisions. Clinical evidence supporting visfatin’s role as a diagnostic marker for CAD is already available, with elevated levels observed in patients with significant CA. However, the paper acknowledges certain limitations, such as the need for more extensive longitudinal studies to validate its potential use in clinical practice to improve early diagnosis and prognosis, ultimately enhancing strategies for preventing cardiovascular disease.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
