Abstract

BackgroundLiterature on the burden and management of atherosclerotic cardiovascular disease (ASCVD) in humanitarian settings is limited. This study aimed to describe patient characteristics and explore both service use and use of recommended secondary prevention drugs in Syrian refugee patients with ASCVD attending two Médecins Sans Frontières (MSF) clinics in Lebanon.MethodsThis study comprised a cross-sectional survey of ASCVD patients attending either MSF clinic over a four-week period in early 2017. Using descriptive statistics, we explored patient demographic characteristics, cardiovascular risk factors and assessed ASCVD secondary prevention medication prescription and patient adherence with a 7-day self-report scale. A retrospective study of routine clinical data explored workload and trends in patient loss to follow-up. We performed logistic regression modelling to explore risk factors for loss to follow-up.ResultsWe included 514 patients with ASCVD in the cross-sectional study, performed in 2017. Most (61.9%) were male and mean age was 60.4 years (95% CI, 59.6–61.3). Over half (58.8%) underwent revascularization and 26.1% had known cerebrovascular disease. ASCVD risk factors included 51.8% with diabetes and 72.2% with hypertension. While prescription (75.7 to 98.2%) and self-reported adherence rates (78.4 to 93.9%) for individual ASCVD secondary prevention drugs (ACE-inhibitor, statin and antiplatelet) were high, the use of all three was low at 41.3% (CI95%: 37.0–45.6). The 5-year retrospective cohort study (ending April 2017) identified 1286 patients with ASCVD and 16,618 related consultations (comprising 24% of all NCD consultations). Over one third (39.7%) of patients were lost to follow-up, with lower risk among men.ConclusionsThe burden of ASCVD within MSF clinics in Lebanon is substantial. Although prescription and adherence of individual secondary prevention drugs is acceptable, overall use of the three recommended drugs is suboptimal. Loss to follow-up rates were high. Further studies are needed to evaluate innovative strategies to increase the use of the multiple recommended drugs, and to increase the retention of patients with ASCVD in the care system.

Highlights

  • Literature on the burden and management of atherosclerotic cardiovascular disease (ASCVD) in humanitarian settings is limited

  • This study aimed to describe the magnitude of the burden of ASCVD in patients seeking care in two Médecins Sans Frontières (MSF) clinics in northern Lebanon, and the characteristics and pattern of care of these patients

  • We explored whether some baseline demographics, time from first visit and clinical factors (ASCVD diagnosis, risk factors) were associated with non-adherence

Read more

Summary

Introduction

Literature on the burden and management of atherosclerotic cardiovascular disease (ASCVD) in humanitarian settings is limited. Cardiovascular diseases (CVDs), cancer, diabetes and chronic lung diseases are the four key NCDs highlighted by WHO [1, 2]. Their burden continues to grow globally, but at a higher rate in low- and middle-income countries (LMICs). Among the 70% (40 million) of global deaths due to NCDs in 2016, CVDs were the leading cause (17.7 million) [2]. Over three quarters of global CVD deaths occur in LMICs, which bear the burden of most premature deaths (under the age of 70) [4]

Objectives
Methods
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call