Abstract
Radiotherapy is an integral part of the cancer treatment, including with mediastinum, breast cancer. In this case, cardiovascular complications of the treatment are quite common. The long-term prognosis can be determined not only by the effectiveness of radiotherapy, but also by cardiovascular risks. A feature of cardiotoxicity of radiation therapy is the high probability of its occurrence in the delayed period of 3–30 years after treatment. The article highlights the results of published epidemiological studies of cardiotoxicity of radiotherapy, as well as the available screening algorithms for cardiovascular complications in patients who underwent radiotherapy. Own clinical observation of the early debut of coronary artery disease after combined chemoradiotherapy of diffuse large B-cell non-Hodgkin lymphoma is presented.
Highlights
Summary Radiotherapy is an integral part of the cancer treatment, including with mediastinum, breast cancer
A feature of cardiotoxicity of radiation therapy is the high probability of its occurrence in the delayed period of 3–30 years after treatment
The article highlights the results of published epidemiological studies of cardiotoxicity of radiotherapy, as well as the available screening algorithms for cardiovascular complications in patients who underwent radiotherapy
Summary
E. Shkolnikova People’s Friendship University of Russia, City Clinical Hospital n. Резюме Радиотерапия является неотъемлемой частью лечения онкологических заболеваний, в том числе при поражении органов средостения, молочной железы. Представлено собственное клиническое наблюдение раннего дебюта ишемической болезни сердца после комбинированной химиолучевой терапии В-крупноклеточной неходжкинской лимфомы. Summary Radiotherapy is an integral part of the cancer treatment, including with mediastinum, breast cancer. In this case, cardiovascular complications of the treatment are quite common. Данная статья содержит анализ результатов опубликованных эпидемиологических исследований кардиотоксичности радиотерапии, а также обсуждение возможных профилактических стратегий и терапевтических мишеней при планировании лучевой терапии. В заключение представлено собственное клиническое наблюдение случая раннего дебюта ИБС с поражением ствола левой коронарной артерии у молодой женщины после комбинированного лечения В-клеточной неходжкинской лимфомы
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