CARDIOVASCULAR CHANGES IN SUBCLINICAL HYPOTHYROIDISM: DESCRIPTIVE OBSERVATIONAL STUDY

Abstract

Thyroid disorders are the most common endocrine disorders in India. Reduced production of thyroid hormone is central feature of clinical state termed as “hypothyroidism”. Iodine deciency remains a common cause of hypothyroidism worldwide. In areas of iodine sufciency, autoimmune disease (Hashimoto's thyroiditis) and iatrogenic causes (treatment of hyperthyroidism) are most common. By denition, subclinical hypothyroidism refers to biochemical evidence of thyroid hormone deciency in patients who have few or no apparent clinical features of hypothyroidism. Subclinical Hypothyroidism is an asymptomatic state in which reduction in thyroid activity is compensated by elevated thyroid stimulating hormone to maintain euthyroid state. Evidence seems to indicate subclinical hypothyroidism is quite prevalent in presumably normal population. Subclinical hypothyroidism is found in 6–8% of women (10% over the age of 60) and 3% of men8. Prevalence increases with age. Methods- This was an observational study done in medical college and hospital. The study was carried out in the duration of 2 years. All OPD and IPD patients of Hospital, diagnosed with subclinical hypothyroidism, during this period, who fullled the inclusion criteria, were included in this study. This study included 54 newly diagnosed patients with subclinical hypothyroidism attending Hospital. Results- In this study maximum patients belong to age group ranging from 18-30 (33.33%). Next to it is age group involving 31-40 (31.48%). While least number of patients comes in age group ranging from 61-70 (9.26%) . Female (74.07%) preponderance compared to males (25.93%). With male having (25.93%). Male to Female ratio is 1:3. Showing female predominance in hypothyroidism. Conclusion- Quite a signicant number of patients were in the prehypertension group. Various life style modications can be advised to prevent them from going to stage I hypertension. Skin changes, Facial pufness, Hoarseness of Voice, cold intolerance, limbs swelling and weight gain these are the symptoms in decreasing order in patients with subclinical hyperthyroidism