Abstract
Accumulating evidence from dietary intervention studies suggest that diets rich in flavanols are causally related to cardiovascular health benefits in humans. In order to consider flavanols as potential candidates for inclusion in future dietary recommendations, it is necessary to assess the efficacy, relevance, and applicability to the general public. Therefore, the pan‐European research consortium FLAVIOLA aimed at investigating the cardiovascular effects of cocoa flavanol (CF) intake in various cohorts representing a broader segment of the healthy population. In particular, we investigated the efficacy of CF from a gender‐ and age perspective in healthy people. Our data demonstrate that CF intake exerts beneficial effects on various accredited cardiovascular endpoints in healthy men and women across all the ages and groups investigated. Taken together, we provide direct evidence for population‐based health benefits, thus supporting a potential role for cocoa flavanols in primary cardiovascular disease prevention and future dietary guidelines.Grant Funding Source: FLAVIOLA Consortium, European Union 7th Framework Program
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