Abstract
Context: Cardiac autonomic dysfunction may develop in patients with polycystic ovary syndrome (PCOS). Purpose: evaluation of cardiovascular autonomic functional modulation by using HRV in females with PCOS. Methodology: Thirty patients with PCOS and 30 healthy female volunteers who were matched for age and body mass index (BMI) were enrolled in the study. Frequency domain power spectral analysis of heart rate variability (HRV) did using non- parametric method of Fast Fourier Transform, using Kubios HRV analysis software. Results: compared to controls females with PCOS demonstrated a significant reduction in Total power of HRV & High frequency (HF) during rest compared to controls (p=0.016) (p=0.00) & significant increase in Low frequency (LF) (p=0.0134) and LF/HF ratio. (p=0.000). Conclusion: we conclude that females with PCOS have altered cardiac autonomic modulation during rest in terms of decreased parasympathetic tone and increased sympathetic tone. Key words: Stress, Parasympathetic tone, Hyperandrogenism, Heart rate variability, Polycystic ovarian syndrome
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