Abstract
The abdominal ganglia of the Limulus central nervous system exert a net inhibitory effect on heart rate. This influence is mediated mainly by the dorsal nerves in the first three ganglia. When the dorsal nerves are sectioned, cardioacceleration results; when these nerves are stimulated, a reduction in rate is obtained. However, cardioaccelerators can be unmasked by splitting a ganglion. This selectively removes the inhibitory output, leaving only a cardioaccelerator influence. Inhibition of bioelectrical activity in the intact abdominal ganglia with GABA also resulted in an increased heart rate, confirming their net inhibitory influence on heart function. Possible models of abdominal ganglia organization are discussed.
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