Abstract

The paper presents the results of the recent studies and research conducted within the Quantum Biological Thermodynamics with Finite Speed on the calculation and interpretation of the Cardio-Pulmonary System performance. Thus, based on the new PV/Px diagram developed for the Cardio-Respiratory System, an original Scheme for calculating the Mechanical Work and Power of the Heart/Lungs has been developed. The new Calculation Scheme allows to study the variation of the Heart and Lungs parameters for each person, in Quantum States and in Processes with and without Quantum Jump. Based on the values calculated in each Stationary State, for the cases studied, the diagrams of the Mechanical Work, of the total Power and the Entropy Source for the Cardio-Pulmonary System, as functions of the Frequencies of the Heart (FH), and the Lungs (FL), the maximum systolic pressure and body mass of the person were thus constructed. The study and interpretation of these diagrams - which are novel elements - provides information on interactions within the Cardio-Pulmonary System or between it and the entire body, particularly useful in bioengineering for optimized and personalized design of artificial organs.

Highlights

  • Experimental partScheme for calculation of Mechanical Work, Power and Source of Entropy of the Cardio-Pulmonary System

  • The paper presents the results of the recent studies and research conducted within the Quantum Biological Thermodynamics with Finite Speed on the calculation and interpretation of the Cardio-Pulmonary System performance

  • The new diagrams constructed, using the values calculated with the discovered analytical formulas, facilitate the study of the variation of the two parameters of the Heart and Lungs, in Stationary Quantum States, customized to each person

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Summary

Experimental part

Scheme for calculation of Mechanical Work, Power and Source of Entropy of the Cardio-Pulmonary System. At a Stroke (oscillation) of the Heart, the Cardiac Output pumped (volume/stroke), results when considering eq (2) as: CO0. CfinlroowwwhtnihcsrhouurwfgaBhc[emtho/esf]tHh-eethamertemcdoeiamalnpcsraoprtsemsesdeenoctfstit,ohSneHo,bavflrot-hotedhtedruucnriricncaugtleiatdsr cone to the Volume variation of the Heart between the sthyesTtoHhleeeacarintrcdwudiltaiharsdctoiraolemw, eanntesdur rdSfavv-c≅teh0eo.0fm2th7eeamnms[eu1dr6fi]aa.cl ecroofsas valve of section of the truncated cone was calculated to respect cardiac output (COo) ejected during the Heart systole:. The current Volume entering into the Lung at an inhalation (Stroke) is:. Where t = 1 min, and for the total Volume entering and leaving the Lungs every minute, an average value of. The mean value of 757 mmHg and 765 mmHg, respectively, were considered in the computational scheme for the Pressures into the respiratory tract and Lungs at inhalation and expiration. The total Mechanical Work of the Lung is calculated taking into account the Pressure losses done by throttling:. Dwdiaahvrm,eL=ree0te:.0rs0ρ7a(6iar 9b=omu1t -.1t1h85e3mwmkeg)iga/hntmded3pra-imvaeairrar ygdeberonofsnictthhyei at 33oC; tracheal (2 x 12.2 mm), secondary ((3 + 2) x 8.3 mm), segmental (8 +7) x approx. and it is

Speed in
Conclusions
The diagrams of the Mechanical Work and the total

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