Abstract
The effects of sour cherry (Prunus cerasus) seed extract on the postischemic cardiac recovery were studied in isolated working rat hearts. Rats were treated with various daily doses of the extract for 14 days then hearts were isolated and subjected to 30 min of global ischemia followed by 120 min of reperfusion. The incidence of ventricular fibrillation (VF) and tachycardia (VT) fell from their control values of 93% and 100% to 50% (NS) and 58% (NS), 17% (P < 0.05) and 25% (P < 0.05) with the doses of 10 mg/kg and 30 mg/kg of sour cherry seed extract, respectively.
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