Abstract
We attempted to investigate cardioprotection of electroacupuncture (EA) for enhanced recovery after surgery on patients undergoing heart valve replacement with cardiopulmonary bypass. Forty-four patients with acquired heart valve replacement were randomly allocated to the EA group or the control group. Patients in the EA group received EA stimulus at bilateral Neiguan (PC6), Ximen (PC4), Shenting (GV24), and Baihui (GV20) acupoints twenty minutes before anesthesia induction to the end of surgery. The primary end point was cardioprotection effect of electroacupuncture postoperatively and the secondary endpoints were quality of recovery and cognitive functioning postoperatively. The present study demonstrated that electroacupuncture reduced the occurrence of complications and played a role of cardioprotective effect on patients after heart valve replacement surgery with cardiopulmonary bypass, and it benefits patients more comfortable and contributes to recovery after surgery. This trial is registered with ChiCTR-IOC-16009123.
Highlights
It is well known that cardiopulmonary bypass and surgical procedure contribute to the myocardial ischemia-reperfusion and are associated with high morbidity and mortality after open heart surgery [1]
Chinese versions of Quality of Recovery-9 (QoR-9) and Mini-Mental State Examination (MMSE) were translated from English version by a medical English expert
We have demonstrated that EA plays a role of cardioprotection including antiarrhythmia, attenuating myocardium injury on patients undergoing heart valve replacement, and reduced sufentanil consumption, the occurrence of PONV, POCD in perioperation, and improved MMSE scores and QOR-9 scores compared to the control group
Summary
It is well known that cardiopulmonary bypass and surgical procedure contribute to the myocardial ischemia-reperfusion and are associated with high morbidity and mortality after open heart surgery [1]. AS is reported [2, 3], the morbidity of cardiovascular adverse events after coronary artery bypass graft (CABG) reached 27.7% in the first year and early postoperation complications with heart valve replacement occurs in 26.6%, including valve-related events (7.0%), arrhythmia (7.8%), and general complications (11.8%). According to the theory of traditional Chinese medicine, the Neiguan (PC6) and Ximen (PC4) acupoints, which belongs to the handjueyin pericardium meridian, which is considered to exert a cardioprotective effect, were reported to decrease myocardial ischemia in patients with heart diseases [5, 7]. PC6 is usually a key acupuncture point for preventing and Evidence-Based Complementary and Alternative Medicine
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