Abstract

A 41-year-old man with right-sided dominant heart failure, dialysis-dependent renal insufficiency, and severe neuropathy of unknown cause was sent to our institution for cardiac examination. An echocardiogram showed reduced left ventricular systolic function and an echo-dense myocardium; therefore, amyloidosis was suspected. However, 2 rectal biopsies failed to show amyloid deposits. Transthoracic echocardiography revealed a severely hypertrophied (interventricular septum, 17 mm; left ventricular posterior wall, 15 mm) and slightly dilated left ventricle with a moderately impaired ejection fraction (see the Movie at http://circ.ahajournals.org/cgi/content/full/113/3/e••/DC1). The right ventricle was also slightly hypertrophied and dilated; both …

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