Abstract

We evaluated systolic and diastolic left ventricular function using computer-assisted analyses of M-mode echocardiograms in 36 young diabetics without clinical evidence of cardiovascular disease. In the older diabetics with longer duration of the disease diastolic function was impaired; isovolumic relaxation and the time between minimum dimension and mitral valve opening were prolonged (p . Rapid diastolic filling and change of dimension between minimum dimension and mitral valve opening were normal. A significant correlation between the mean HbA, averaged over the last two years and the isovolumic relaxation period (p could be shown. Fractional shortening as parameter of systolic function showed an inverse relation to the mean HbAl(p<.0008), thus systolic and diastolic dysfunction occurs depending on the quality of metabolic control.

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