Abstract
Results 82,5% (n = 28) had hard combined CHD, 82,4% (n = 28) high pulmonary hypertension, all patients heart failure. In 20,6% (n = 6) patients heart catheterization was performed. 6 (20,6%) kids received only medical treatment: 2 (5,8%) inoperable, 3 (8,8%) medical preparation for surgery due to PH, 1 (2,9%) no need of surgery. 28 (82,4%) patients were operated on. 26 (92,8%) were open heart cases. 57,6% (n = 15) underwent septal defects (ASD, VSD) plasty at median age of 12 ± 3 months. In 42,3% (n = 11) AVSD was corrected at median age of 6 ± 1 month. In 7 patients (23,6%) postoperative period was complicated by: DIC syndrome (57,1%), sepsis (28,6%), chylothorax (14,3%). 30-day in hospital mortality occurred in 3 (10,7%) cases: 1 (14,3%) – due to intractable pulmonary hypertensive crisis; 1 (14,3%) – sepsis; 1 (14,3%) – sepsis associated with DIC syndrome. Neither late death nor any residual defects requiring reoperation were detected at follow up.
Highlights
The number of children with Down syndrome (DS) in general population reaches 4,8-7,0%
There were 19 (56,0%) boys and 15 (44,0%) girls aged from 4 months to 18 years (20 month ± 2 month)
In 42,3% (n = 11) AVSD was corrected at median age of 6 ± 1 month
Summary
The number of children with Down syndrome (DS) in general population reaches 4,8-7,0%. More than 45,0% of them have different forms of congenital heart diseases (CHD), which is the main death cause in this patient group under two years of age. The purpose of this study was to analyze details of perioperative period in children with DS undergoing CHD repair
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