Abstract
Chronic kidney disease (CKD) represents a complex and multifaceted clinical condition characterized by its intricate interaction with multiple organ systems. Among the systemic manifestations of CKD, the impact on the cardiovascular system is particularly profound. This article delves into the intricate relationship between CKD and cardiac strain, exploring the paradoxical nature of myocardial function in the context of renal dysfunction. We navigate the epidemiological landscape, describe pathophysiological mechanisms, investigate diagnostic modalities, and explore current and emerging therapeutic strategies aimed at controlling cardiac strain in CKD. This comprehensive analysis not only sheds light on the cardiac complexities within the CKD setting, but also underscores the need for a holistic approach to improve patient outcomes.
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