Abstract
We read with interest the 2 recent articles in The American Journal of Cardiology related to depression and acute coronary syndromes. 1 Carney R.M. Blumenthal J.A. Catellier D. Freedland K.E. Berkman L.F. Watkins L.L. Czajkowski S.M. Hayano J. Jaffe A.S. Depression as a risk factor for mortality after acute myocardial infarction. Am J Cardiol. 2003; 92: 1277-1281 Abstract Full Text Full Text PDF PubMed Scopus (196) Google Scholar , 2 Swenson J.R. O'Connor C.M. Barton D. Van Zyl L.T. Swedberg K. Forman L.M. Gaffney M. Glassman A.H. Sertraline Antidepression Heart Attack Randomized Trial (SADHRT) GroupInfluence of depression and effect of treatment with Sertraline on quality of life after hospitalization for acute coronary syndrome. Am J Cardiol. 2003; 92: 1271-1276 Abstract Full Text Full Text PDF PubMed Scopus (117) Google Scholar One article demonstrated that depression was associated with a 2.5-fold increased risk of all cause mortality 1 year after acute myocardial infarction 1 Carney R.M. Blumenthal J.A. Catellier D. Freedland K.E. Berkman L.F. Watkins L.L. Czajkowski S.M. Hayano J. Jaffe A.S. Depression as a risk factor for mortality after acute myocardial infarction. Am J Cardiol. 2003; 92: 1277-1281 Abstract Full Text Full Text PDF PubMed Scopus (196) Google Scholar and the second demonstrated that sertraline therapy was associated with significant improvements in multiple quality-of-life (QoL) domains in patients with acute coronary syndromes and recurrent depression. 2 Swenson J.R. O'Connor C.M. Barton D. Van Zyl L.T. Swedberg K. Forman L.M. Gaffney M. Glassman A.H. Sertraline Antidepression Heart Attack Randomized Trial (SADHRT) GroupInfluence of depression and effect of treatment with Sertraline on quality of life after hospitalization for acute coronary syndrome. Am J Cardiol. 2003; 92: 1271-1276 Abstract Full Text Full Text PDF PubMed Scopus (117) Google Scholar Although we agree with both articles on the high prevalence of depression in patients after major cardiac events and that this adversely affects recovery after these events, we were disappointed that neither article emphasized the potential role of nonpharmacologic measures, particularly cardiac rehabilitation and exercise training programs, to improve depression and QoL.
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