CARDIAC REGIONAL FUNCTION OF YOUNG SPORTSMEN WITH FALSE TENDONS IN THE LEFT VENTRICLE

Abstract

The aim of the study is to evaluate cardiac regional function of young athletes with false tendons (FT) in the left ventricle (LV). The focus was on mechanical asynchrony in LV wall. Forty-seven young athletes (mean age 20.2 ± 2.9 years) with connective tissue dysplasia syndrome underwent transthoracic echocardiography. To formalize FT topology, the 3D-model of LV geometry was reconstructed based on three short-axis sections and one long-axis section of LV. On average, 4.0 ± 1.0 FT with different localization and orientation in LV were determined. Cardiac function was estimated in 12 regions at LV long-axis section in the course of complete heart cycle. RMS variations of the regional systolic function duration (dT) and the variation coefficient of regional ejection fraction (Cv r-EF) for 12 regions served as measures of the mechanical asynchrony. Wide variety of asynchrony parameters was obtained. The value of dT varied from 24.2 to 84.1 ms (40.4 ± 27.8 ms); Cv r-EF — from 8.0% to 42.0% (20.83 ± 8.35%). Significant correlations between total number of FT per heart and dT (r = 0.396; P < 0.01) and between median transverse FT (connect interventricular septum and lateral LV wall) and Cv r-EF (r = 0.301; P < 0.05) were found. Detailed analyses of FT morphology with respect of LV regional function peculiarities showed that higher extent of asynchrony associates with the transverse and oblique FT mainly located at basal and/or medial portions of LV chamber.