Abstract
ObjectiveWe have reviewed the medical histories of 4 patients who underwent operations between November 2004 and February 2011 at Changhai Hospital for cardiac papillary fibroelastoma.MethodsDiagnosis was demonstrably suggested by echocardiography. Tumor locations were mitral valve (1), left atrium (1), and aortic valve (2). Indications for operation were previous cerebrovascular accident for the mitral tumor, incidental apopsychia and giant mobile mass for the left atrium, ingravescent chest tightness and palpitations for the first aortic tumor, and severe regurgitation of aortic valve for the second aortic tumor. The study was approved by the Changhai Hospital Ethics Committee, and the consent from the patients or their immediate family was obtained.ResultsSurgical excision with necessary valve replacement operations was performed in all cases. All patients had uneventful postoperative recoveries. No evidence of regurgitation or recurrence was seen on echocardiography at follow-up.ConclusionsDespite their histologically benign aspect, cardiac papillary fibroelastomas should be removed because of potential embolic complications.
Highlights
Cardiac papillary fibroelastoma (CPFE) is rarely in literature as a primary cardiac neoplasm of unknown pathogen [1]
The incidence of primary cardiac tumors is reported to be less than 0.3% in autopsy series, and approximately 50% of them are cardiac myxomas [2,3]
We report 4 cases in this paper to demonstrate the complications, pathological characteristics of CPFE and the intraoperative findings
Summary
Cardiac papillary fibroelastoma (CPFE) is rarely in literature as a primary cardiac neoplasm of unknown pathogen [1]. Though many papillary fibroelastomas may not cause symptoms, early diagnosis of CPFE is of prior importance to prevent patients from fatal complications [4]. The patient was in sinus rhythm while presenting a II/ 6 systolic murmur in heart apex. Transthoracic echocardiography revealed multiple mobile masses on the mitral valve (Figure 1), left ventricle and left ventricular outflow tract.
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