Abstract
Cardiac myxoma with glandular elements is extremely rare cardiac myxomas that show glandular differentiation, the pathogenesis of which is unknown. The present case study reports a case of glandular cardiac myxoma. A 21-years-old female presented with left atrial mass which was surgically resected and sent for histopathological examination. Microscopically, there were well formed mucinous glands in a background of cardiac myxoma and hence cardiac myxoma with glandular elements was confirmed. Though rare, it should always be differentiated from metastatic adenocarcinoma.
Highlights
Cardiac myxoma is the most common primary tumour of the heart which is derived from pluripotent mesenchyme and it is characterized by presence of abundant myxoid matrix with embedded “myxoma” cells.[1]
No mitosis or necrosis was identified. These features were consistent with a glandular cardiac myxoma
Known as cardiac myxoma with glandular component is extremely rare; only 39 cases being reported in literature till 2007.5 The most common location of cardiac myxoma is left atrium, even though some are occasionally found in the right atrium or ventricles.[6]
Summary
Cardiac myxoma is the most common primary tumour of the heart which is derived from pluripotent mesenchyme and it is characterized by presence of abundant myxoid matrix with embedded “myxoma” cells.[1]. Cardiac myxoma is the most common primary tumour of the heart which is derived from pluripotent mesenchyme and it is characterized by presence of abundant myxoid matrix with embedded “myxoma” cells.[1] Majority of the patients are within the age range of 30-60 years. The most common site is the left atrium (85-90% cases) arising from endocardium of the atrial septum near the fossa ovalis.[2] It occurs sporadically in most of the cases and may be associated with autosomal dominant myxoma syndrome, in which cases, the recurrence rate is higher.[3] The clinical presentation is diverse and depends predominantly on the location of the tumour.
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