Abstract
Background: Cardiac myxoma is a very rare heart tumor which presents as life threatening mass in cardiac chamber. The tumor may present with vague symptoms which can lead to delay in diagnosis. Methods: 22 patients underwent complete excision of intracardiac myxoma between January 2011 and December 2020. Majority of the patients were females (60%) with mean age of 48.9 years who presented with symptoms of dyspnea on exertion. 3 patients had significant complications due to myxoma. 2 presenting with tumor embolism and limb ischemia while 1 patient presented with pulmonary edema. All patients were diagnosed by echocardiography which helped in evaluation of size and extent of tumor. Majority of patients underwent trans-septal biatrial approach for tumor excision. Results: 95% of patients survived the operation. The mean tumor size excised was 5.0 ± 1.6 cm in the largest diameter. 11 patients had sessile tumor while 1 patient had dumb bell tumor occupying both atria. 15 patients were surviving the operation while 2 deaths happened after 6 years of surgery. Conclusion: Cardiac myxomas are rare tumors which can cause severe systemic and cardiac symptoms in patients. Early diagnosis and immediate surgical management give excellent early and long-term results.
Highlights
Primary Cardiac Tumors of heart are rare tumors with life time incidence of0.0017% to 0.03%
75% - 80% of primary cardiac tumors are benign with cardiac myxoma the most common amongst them
More than 90% of these tumors are seen in left atrium arising from the Fossa ovalis of inter atrial septum [1] [2] [3]. Genetic association of these tumors has been found in patients of Carney complex due to mutation of PRKAR1A gene
Summary
More than 90% of these tumors are seen in left atrium arising from the Fossa ovalis of inter atrial septum [1] [2] [3]. The clinical manifestation of this tumor presents an important diagnostic challenge due to insidious onset. These patients give vague symptoms of dyspnea, chest pain and carry high risk of systemic embolization with cerebral or peripheral infarctions due to large mobile myxoma in left or right ventricle which may cause sudden death due to prolapse through valve [4] [5] [6] [7] [8]. The present study summarizes 10 years of clinical experience with consecutive series of 22 patients operated for Cardiac myxomas
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