Abstract
Objective: Diabetic cardiomyopathy (DC) is a myocardial disease characterized by myocyte hypertrophy, interstitial fibrosis, protein glycosylation and intra-myocardial micro-angiopathy due to prolonged exposure of myocardial tissues to hyperglycemia in diabetes mellitus (DM) patients. Alteration in cardiac function can be non-invasively assessed via echocardiography. The early recognition of cardiac dysfunction can prevent the symptomatic heart failure in DM patients. The study aimed at evaluating cardiac function in uncomplicated type 2 diabetes mellitus.
 Materials And Methods: Sixty Type 2 DM patients without any feature of the coronary arterial disease (CAD), hypertension, nephropathy and respiratory illness were enrolled in the study and compared with the sixty age matched healthy controls. Echocardiographic assessment was done in all subjects to evaluate the cardiac function.
 Results: Diastolic dysfunction was more common in diabetic patients when compared with normal healthy population. Systolic dysfunction progresses with age of the diabetic patient.
 Conclusion: Echocardiography is a simple noninvasive cost effective test for detecting cardiac dysfunction in Type 2 DM patients and should be applied to detect early Left ventricular(LV) dysfunction so that corrective measures may be initiated early and cardiac functions may be preserved for long.
 Bangladesh Journal of Medical Science Vol.18(2) 2019 p.211-215
Highlights
Diabetes Mellitus (DM) is emerging as a massive outbreak in developed and developing countries; inflicting considerable human suffering
Diabetic cardiomyopathy leads to heart failure and is characterized functionally by decreased or preserved systolic function, impaired diastolic function, ventricular dilation, hypertrophy of myocytes and myocardial fibrosis.[3]
Several researcher have shown cardiac dysfunction leading to heart failure in Type 2 DM patients in absence of coronary arterial disease and hypertension.[9,10]
Summary
Diabetes Mellitus (DM) is emerging as a massive outbreak in developed and developing countries; inflicting considerable human suffering. India is one of the 6 countries of the IDF (International Diabetes Federation) South-East Asia region with 69.1 million cases of diabetes in 20151 Diabetic patients are prone to various complications involving retina, kidneys, nerves and cardiovascular system that cause morbidity and premature mortality It is an independent risk factor for cardiovascular diseases (CVD) and cardiac complications are responsible for three-fourths of all diabetic mortality.. Several researchers have indicated major risk factors for cardiovascular disease act as independent contributors to CVD in patients with diabetes.. Several researchers have indicated major risk factors for cardiovascular disease act as independent contributors to CVD in patients with diabetes.3 These risk factors include smoking, high blood pressure, and dyslipidemia. Mean duration of diabetes in the study group was 5 years
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