Abstract

Aim: to assess cardiac conduction disturbances after transcatheter aortic valve replacement (TAVR) with the “MedLab-KT” device in early postoperative period.Methods. The study comprised 80 patients (mean age 72,4±5,1 years; 42,5% males) undergoing successful TAVR with the “MedLab-KT”. Before operation, all patients were evaluated with 12-lead ECG and 24-hour Holter monitoring, transthoracic and transesophageal echocardiography, computed tomography, coronarography. In 29 (36,3%) patients cardiac conduction abnormalities were detected before operation: 1st degree atrioventricular (AV) block was found in 17 patients, including concomitant left anterior hemiblock (LAH) in 7 patients, and right bundle branch block (RBBB) in 3 (LAH+RBBB). Second degree AV-block type 1 was found in 1 patient. LAH – in 2, RBBB – in 5, and left bundle branch block (LBBB) – in 4. Post-operative follow-up was limited to hospital stay (13,4±7,4 days).Results. De-novo conduction abnormalities (reversible and irreversible) were detected in 41 patients (51,3%). Post-TAVR complete AV-block was found in 6 (7,5%) patients, and required temporal pacing. In 4 of those patients AV-block was transient and resolved within 1 day. In 2 (2,5%) patients permanent pacing was required due to irreversible distal AV-block. In one case AV-block developed 2 days after TAVR in a patient with pre-existent 1st degree AV-block in combination with LAH+RBBB. Another patient developed complete AV-block at 3d day after TAVR; in this case there was pre-existent 1st degree AV-block plus LAH. Persistent interventricular block was found in 35 patients: complete LBBB - in 17 patients and complete RBBB – in 1 patient. There were no statistically significant predictors of conduction disturbance development following TAVR.

Highlights

  • In 29 (36,3%) patients cardiac conduction abnormalities were detected before operation: 1st degree atrioventricular (AV) block was found in 17 patients, including concomitant left anterior hemiblock (LAH) in 7 patients, and right bundle branch block (RBBB) in 3 (LAH+RBBB)

  • Persistent interventricular block was found in 35 patients: complete left bundle branch block (LBBB) - in 17 patients and complete RBBB – in 1 patient

  • There were no statistically significant predictors of conduction disturbance development following transcatheter aortic valve replacement (TAVR)

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Summary

Introduction

У 29 (36,3%) пациентов до оперативного лечения имелись нарушения проводимости. 1 типа выявлена у 1 больного, БПВЛНПГ - у двух, БПНПГ - у пяти и блокада ЛНПГ (БЛНПГ) - у четырех человек. Постпроцедурная полная АВБ, потребовавшая временной ЭКС, развилась у 6 (7,5%) пациентов. Лишь 2 (2,5%) пациентам после ТПАК был имплантирован постоянный ЭКС по поводу необратимой полной дистальной АВБ. В первом случае полная АВ блокада развилась на 2 сутки после оперативного лечения у пациента с АВБ 1 степени в сочетании с БПВЛНПГ и БПНПГ. Во втором случае полная АВБ развилась на 3-и сутки после ТПАК у пациента с изначально имеющейся АВБ 1 степени в сочетании с БПВЛНПГ. У 35 пациентов отмечались стойкие нарушение проводимости в виде развития блокад ножек пучка Гиса. Из них у 17 пациентов отмечалось развитие полной БЛНПГ, у 17 - БПВЛНПГ и в 1 случае - БПНПГ. Aim: to assess cardiac conduction disturbances after transcatheter aortic valve replacement (TAVR) with the “MedLab-KT” device in early postoperative period

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