Cardıac Arrhythmıas and Magnesıum

Abstract

Magnesium is one of the intracellular cations that play an essential role in many biological reactions. Intracellular magnesium is an important cofactor for various enzymes, carriers and nucleic acids required for normal cellular function, energy metabolism and replication. It is required for normal cardiac electrical activity. Magnesium deficiency can cause many disorders including cardiac arrhythmias. Intravenous magnesium has long been used in the treatment and prevention of arrhythmia since it has a high therapeutic to toxic ratio and minimal negative inotropic effect. Many studies have shown a beneficial effect of intravenous Mg administration in tachycardia attacks. But this positive effect varies according to the type of tachycardia. Especially in the treatment of supraventricular tachycardia and in the acute treatment of atrial fibrillation with a ventricular rate ≤ 100/ min, the beneficial effects are more pronounced. The administration of intavenous magnesium appears to be useful in the treatment and prevention of cardiac arrhythmias and is a common component of a complex antiarrhythmic treatment.