Abstract
1. Carcinoma may develop in areas of chronic regional enteritis, and a cause and effect relationship probably exists. 2. The carcinoma in regional enteritis differs from primary small bowel carcinoma in a) younger age group, b) higher incidence in the ileum, c) more frequently multifocal or diffuse, d) worse prognosis. 3. The carcinoma is rarely diagnosed preoperatively, either clinically or radiographically, and is frequently not diagnosed at surgery. 4. The most common symptom of a carcinoma in regional enteritis is intestinal obstruction. 5. In the presence of chronic regional enteritis, progressive symptoms of intestinal obstruction should be a warning, and surgery should not be delayed. 6. The limited use of bypassed segments in regional enteritis may make the diagnosis of complicating small bowel carcinoma less difficult.
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