Carcinoma mioepitelial originado sobre un adenomioepitelioma de mama

Abstract

IntroductionAdenomyoepithelioma (AME) of the breast is an uncommon tumour that can undergo malignant transformation in one or more of its components, whether epithelial and/or myoepithelial. Standardisation of diagnosis and treatment is hampered by the numerous existing classifications, variability in the nomenclature to refer to the same entity, and the rarity of this disease. Case reportWe present a case of myoepithelial carcinoma arising in an AME. AME is more common in postmenopausal women. The characteristic finding on imaging tests is the presence of a nodular lesion with circumscribed borders, which is more frequent in the central breast region. Immunohistochemical techniques are essential to establish an accurate diagnosis. DiscussionTreatment of myoepithelial carcinoma arising in an AME consists of correct resection of the lesion with adequate surgical margins. The need for axillary lymph node staging is controversial, given that, in most lesions, the definitive diagnosis is not given by biopsy but rather by histopathological analysis of the surgical specimen.