Abstract

Nonhomogeneous leukoplakia, also referred to as erythroleukoplakia (ELP), is a rare lesion of the oral mucosa. It is reported a case of a female patient, melanoderma, farmer, diabetic, and smoker, which was sought the service reporting gingival inflammation 2 years ago. Intraoral examination revealed white plaque, interspersed with reddish and melanocytic area involving on the left side of the hemipalate, and eritroleucoplastic plaque on the back of the tongue measuring 1.5 x 1.3 cm. Both lesions were biopsied, and slides section obtained from the palatal showed hyperkeratosis and acanthosis (HA) with mild dysplasia, and from the tongue it was HA with severe dysplasia. After 1 year of follow-up a new biopsy was carried in the tongue lesion and slides sections showed an in situ carcinoma. This case illustrates the importance of an intensive follow-up at short intervals because ELP recurrences can occur with more dysplastic changes.

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