Carcinoma Expleomorphic Adenoma of the Submandibular Gland

Abstract

ABSTRACT Background and objectives Carcinoma expleomorphic adenoma (CXPA) is a rare neoplasm of the salivary gland which arises in the epithelial component of a pleomorphic adenoma. It is not automatically a high-grade tumor as is traditionally suggested and should be further qualified as to type, grade of carcinoma and extent, since intracapsular and minimally invasive tumors behave favorably. Setting Department of Head and Neck oncosurgery, Kidwai Memorial Institute of Oncology, Bengaluru. Case Report A 38-year-old female was referred to our outpatient clinic with history of a painless swelling in the left side of the neck since 8 years. Fine needle aspiration revealed carcinoma of the submandibular gland. Contrast enhanced CT revealed a large heterogeneously enhancing mass lesion in the submandibular fossa with the gland not seen separately. Lymph nodes in level Ib and II were enlarged. Excision of the tumor revealed CXPA with foci of high grade mucoepidermoid carcinoma. Conclusion CXPA should no longer be considered a specific diagnosis but a category in which the carcinoma should be typed, graded and quantitated to impart more prognostically and therapeutically relevant data for efficient management. How to cite this article Naik SM, Shenoy AM, Chavan P, Halkud R, Biswas S, Kalloli M, Gupta S, kudpaje A. Carcinoma Expleomorphic Adenoma of the Submandibular Gland. J Postgrad Med Edu Res 2013;47(3):162-166.