Abstract
Carcinoma ex pleomorphic adenoma is a high-grade salivary gland cancer in which malignant transformation occurs in a previously benign pleomorphic adenoma. A 56-year-old woman attended the Hospital Dental Center presenting an exophytic sessile nodule on the hard palate. She had been diagnosed with a pleomorphic adenoma in this region a year prior. Computed tomography revealed a hypodense image in the left region of the hard palate. Microscopic examination demonstrated a neoplasm composed of epithelial and myoepithelial cells, organized in ductal structures, cords, and nests. Islands with epithelial cells, presenting nuclear pleomorphism, clear cells, and cystic spaces bounded by mucous cells characterized the malignant component. Keratin pearls were also present in the center of some islands. The specimen's margins were compromised. A final diagnosis of carcinoma ex pleomorphic adenoma was obtained. The patient was referred for removal of surgical margins and remains to undergo clinical follow-up.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
