Abstract
Introduction of prostate‐specific antigen (PSA)–based screening for prostate carcinoma has led to a significant increase in the detection of prostate carcinoma. Prostate core needle biopsy remains the gold standard as a diagnostic tool with which to ascertain disease status. In this issue of Cancer, Demura et al. challenge some commonly accepted concepts regarding the zonal distribution of prostate carcinoma and explore the distribution of carcinoma cores within the prostate as well as the potential impact of a systematic, ultrasound‐guided transperineal template biopsy in improving carcinoma detection rates.
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