Abstract

SUMMARY Although dermoid cysts (Mature cystic teratoma) of the ovary are almost always benign tumors, the rare development of cancer deserves emphasis. A case of carcinoid tumor of insular type is presented. The small focus of carcinoid tumor was found incidentally in a resected dermoid cyst. Histologically, the tumor had thick fibrous septa among the cell nests. The tumor revealed argyrophylia by Grimelius satin. The immunohistochemical studies demonstrated positivity for Chromogranin A, Synaptophisin, NSE, Prostatic Acid Phosphatase (PAP) and Substance-P. This case is considered to be a rare ovarian carcinoid arising from a dermoid cyst without an association of struma ovarii. Immunohistochemistry will be helpful in demonstrating the neuroendocrine nature of the tumor cells.

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