Abstract
Carboxytherapy is a minimally invasive method used not only in esthetic medicine. It is defined as the transcutaneous or subcutaneous application of carbon dioxide gas. The treatment exerts effects on various levels including improvement of tissue oxygenation, vasodilatation, stimulation of fibroblasts, and antimicrobial activity. In this review, we will focus on facial and neck esthetics, localized adiposities and cellulite, and scars and stretch marks. We discuss reported evidence for these indications and safety issues. We also mention possible combinations with other treatments. In general, a repeated application is necessary to achieve desired results.
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