Carbonylative cycloaddition for the synthesis of medium-sized carbo- and heterocycles

Abstract

Highly functionalized medium-sized carbo- and heterocycles are of great interest for the synthesis of natural molecules and their analogs, yet their synthesis remains challenging. Cycloaddition reactions have proven to be quite efficient methods towards them. This review focuses on the use of carbonylative cycloaddition for the synthesis of the most challenging ring sizes, i.e., seven-, eight-, and nine-membered rings.