Abstract

Imbalance in the levels of monoamine neurotransmitters have manifested in severe health issues. Electrochemical sensors have been designed for their determination, with good sensitivity recorded. Carbon-based quantum dots have proven to be an important component of electrochemical sensors due to their high conductivity, low cytotoxicity and opto-electronic properties. The quest for more sensitive electrodes with cheaper materials led to the development of electrochemical sensors based on carbon-based quantum dots for the detection of neurotransmitters. The importance of monoamine neurotransmitters (NTs) and the good electrocatalytic activity of carbon and graphene quantum dots (CQDs and GQDs) make the review of the efforts made in the design of such sensors for monoamine NTs of huge necessity. The differences and the similarities between these two quantum dots are highlighted prior to a discussion of their application in electrochemical sensors over the last ten years. Compared to other monoamine NTs, dopamine (DA) was the most studied with GQDs and CQD-based electrochemical sensors.

Highlights

  • Every human action has a connection with the nervous system

  • Reviewed the synthesis and the effort into the progress made in the design of electrochemical sensor and biosensors for the of neurotransmitters fifteen years (2000–2015), with special attention on the various application detection of Carbon quantum dots (CQDs) and Graphene quantum dots (GQDs) inover electrochemical, chemiluminescence, photoluminescence and materials applied for the production of the sensors

  • These classes of quantum dots (GQDs and CQDs) have good optoelectronic liquid conferred a positive charge on the graphene sheets, which led to the electrostatic attraction for properties, whichwith makes themcharged applicable numerous In processes where fluorescence is required

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Summary

Introduction

Every human action (voluntary or the converse) has a connection with the nervous system. Put good effort into discussing the progress made in the design of electrochemical sensor and biosensors for the detection of neurotransmitters over fifteen years (2000–2015), with special attention on the various materials applied for the production of the sensors Ribeiro and his crew did not refer to the application of quantum dots in their lengthy review. Ribeiro et al [68] put good of biomolecules, as discussing well as the characterization of QDs. reviewed the synthesis and the effort into the progress made in the design of electrochemical sensor and biosensors for the of neurotransmitters fifteen years (2000–2015), with special attention on the various application detection of CQDs and GQDs inover electrochemical, chemiluminescence, photoluminescence and materials applied for the production of the sensors. Royal graphene quantum dots.Society of Chemistry); (d) Heteroatom (blue atom) doped graphene quantum dots

Graphene and Carbon Quantum Dots
Similarities and GQDs
Differences between GQDs and CQDs
Electrochemical Methods
Cyclic Voltammetry
Cyclic voltammogram showing
Square
Squareare
Linear
Electrode Fabrication
Preparation
Modification of Carbon Paste Electrode
Modification of Screen-Printed Electrodes
Mechanism of Monoamine Neurotransmitters Detection
A general proposed mechanism catecholamine neurotransmitters oxidation
Electrochemical
Electrochemical Performance in Dopamine Determination
13. Electrochemical
15. Electrochemical
Findings
Carbon-Based QDs and Monoamine Neurotransmitters
Full Text
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