Abstract

AbstractCarbon-based nanomaterials (CBNs) are unique technological tools used for biomedical applications. The study of CBNs in drug and gene delivery systems has attracted important attention due to their unique chemical and physical properties. The unique properties include high mechanical strength, increased conductivity, attractive optical properties, enhanced surface-to-volume ratio, chemical versatility, ease of functionalization, and biocompatibility. These unique properties of CBNs have led to their consideration in novel drug and gene delivery systems. CBNs are composed of carbon nanotubes, fullerenes, graphite oxide, and graphene quantum dots. CBNs are effectively taken up by many different cell types using different mechanisms. As a result, CBNs have acted as carriers of various drugs and genes. An ideal CBN carrier for target drug and gene delivery systems should have target effects and adsorption for targeted drugs or genes. This ensures that the genes or drugs are transported to the target site. Furthermore, the carriers must successfully release the drugs or genes in the target sites to develop an effective treatment. This chapter summarizes the most recent studies in developing CBNs for targeted drug and gene delivery systems to improve the treatment of diseases.KeywordsCarbon-based nanomaterials Drug delivery Gene delivery Target site

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