Carbon-paste biosensors array for long-term glucose measurement

Abstract

An amperometric glucose biosensor based on a new mediator and carbon paste acts at 0-08 V vs. an Ag/AgCl electrode in situ and exhibits a linear response up to 16 mM of glucose. The measurements are performed on freshly renovated electrode surfaces, and every sensor can be used for 100 measurements. The long-term stable biosensors were obtained using stabilized glucose oxidase and an array of biosensors. The application of a chemometric method permits exploitation of the biosensor during a period of more than 166 days at 35°C and relative humidity 75%. The relative error of chemometric prediction was less than 5·4%, and the response changes less than 0·15% per week.