Carbon-ion Radiation Therapy for Locally Advanced Primary or Postoperative Recurrent Epithelial Carcinoma of Lacrimal Gland: A Phase I/II Dose-escalation Study

Abstract

Conclusions: Long-term result of C-ion RT for choroidal melanoma at our institute was satisfactory, even with tumors of unfavorable size or site. This study suggests tumor size, distance from optic disc, and number of port are related to NVG occurrence; distance from optic disc is related to survival and distant metastasis. CT based two-port C-ion RT can be useful to reduce irradiated volumes of iris ciliary body and resulting risk of NVG. Author Disclosure: S. Toyama: None. H. Tsuji: None. N. Mizoguchi: None. T. Kamada: None. H. Tsujii: None. S. Tokumaru: None. Y. Onishi: None.