Carbon Dot Based Sensing of Dopamine and Ascorbic Acid

Upama Baruah,Neelam Gogoi,Devasish Chowdhury,Achyut Konwar,Manash Jyoti Deka,Gitanjali Majumdar

doi:10.1155/2014/178518

Upama Baruah, Neelam Gogoi + Show 4 more

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https://doi.org/10.1155/2014/178518

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Abstract

We demonstrate carbon dot based sensor of catecholamine, namely, dopamine and ascorbic acid. Carbon dots (CDs) were prepared from a green source: commercially available Assam tea. The carbon dots prepared from tea had particle sizes of ∼0.8 nm and are fluorescent. Fluorescence of the carbon dots was found to be quenched in the presence of dopamine and ascorbic acid with greater sensitivity for dopamine. The minimum detectable limits were determined to be 33 μM and 98 μM for dopamine and ascorbic acid, respectively. The quenching constants determined from Stern-Volmer plot were determined to be 5 × 10−4 and 1 × 10−4 for dopamine and ascorbic acid, respectively. A probable mechanism of quenching has been discussed in the paper.

Highlights

Carbon dots are recently being used as one of the most efficient and stable nanoprobes for various types of analytes owing to their easy preparation, photostability, and low toxicity compared to other heavy metals containing quantum dots [1, 2]
This carbon dot solution was used as a material for optical sensing of dopamine and ascorbic acid as shown in Scheme 1
The carbon dots prepared from tea were characterized by dynamic light scattering (DLS) technique, scanning electron microscopy (SEM), powder XRD measurement, UVVisible absorption spectroscopy, fluorescence spectroscopy, and Fourier transform infrared spectroscopy

Summary

Introduction

Carbon dots are recently being used as one of the most efficient and stable nanoprobes for various types of analytes owing to their easy preparation, photostability, and low toxicity compared to other heavy metals containing quantum dots [1, 2] They belong to the family of carbon nanomaterials and show characteristic bright blue or green fluorescence under UV light irradiation. To the best of our knowledge, such fluorescence based techniques using carbon nanomaterials are very limited in case of these neurotransmitters Among these very limited numbers of attempts, Qu and coworkers demonstrated the use of carbon dots for the detection of iron and dopamine [6]. A possible mechanism is proposed for the observed result

Experimental Section

Results and Discussion

Conclusion