Caractéristiques cliniques, biochimiques et épidémiologiques d’une macro-ASAT précédant le diagnostic de maladie inflammatoire chronique de l’intestin de plusieurs années

Abstract

IntroductionAn isolated elevation of aspartate aminotransferase (AST) is a diagnostic issue. Macro-aspartate aminotransferase (macro-AST) corresponds to the formation of complexes between AST and immunoglobulins. Case reportWe report the case of a patient with macro-AST identified several years before the onset of inflammatory bowel disease (IBD). A 6-year retrospective analysis in our laboratory identified only one case out of 42 540 adult patients. ConclusionThe objective of this work is to increase awareness of this benign disorder among clinicians and biologists, as well as to aid in prescribing only the required tests.