Características anatómicas, biomecánicas y aberrométricas de la córnea de pacientes con síndrome de Marfan

Abstract

ObjectiveTo know the anatomical (mean keratometry, central pachimetry), optic (corneal aberrations represented by Zernike polynomials) and biomechanical (corneal hysteresis, and corneal resistance factor) characteristics in patients with Marfan syndrome. Material and methodsProspective, transversal and observational study. We study patients with confirmed diagnosis of Marfan syndrome. The anatomical and aberrometrical characteristics was measured with otating Scheimpflug Camera (Pentacam, Oculus) and the biomechanical characteristics with ocular response analyzer (Reichert). The ocular response analyzer measures was made 4 times and represented by his average. All the studies was made by the same examiner. ResultsTwenty eyes of 10 patients with confirmed diagnosis of Marfan syndrome was studied. 60% was male with an average age of 24±10.79 years (range, 11-39). Three eyes of 2 patients was aphakic because a spontaneous posterior lens dislocation, of the other 17 eyes 100% subluxation of the lens. Mean simK was 40.49±1.54D (range, 38.7-42.7) 80% had less than 42D. Average central corneal thickness was 562±37.23μm (range 506-626μm). All the patients had a patological aberration coefficient 1.55±0.37 (range, 1.1-2.5). Corneal hysteresis was 9.13±1.49mmHg (range, 7.1-12) and corneal resistance factor 9.09±2.41mmHg (range, 4.8-13.6). ConclusionsIn our studied group, the corneas of Marfan syndrome patients presents a flat corneas with a normal pachymetry and biomechanical properties but with a abnormal aberration coefficient values