Caracterización de especies del género Malassezia en pacientes con dermitis seborreica y en controles

Elizabeth Rendic O,Cristina Díaz J,Félix Fich S

doi:10.4067/s0034-98872003001100010

Elizabeth Rendic O, Cristina Díaz J + Show 1 more

Open Access

https://doi.org/10.4067/s0034-98872003001100010

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Abstract

The yeast Malassezia spp has an established etiological role in pityriasis versicolor, folliculitis, systemic infections and onychomycosis.To assess the presence of Malassezia spp in patients with seborrheic dermatitis (SD), to find a correlation between Malassezia spp count and the severity of the disease and to compare the prevalence of the different Malassezia species in SD patients and subjects without skin lesions.Scrapings of the face from 81 patients with SD (69 males) and 79 subjects (54 males) without skin lesions were obtained for a direct microscope examination and yeast culture.The yeast Malassezia was found in 76% of SD patients and in 82% of subjects without skin lesions. There was a positive correlation between the number of yeasts found on direct examination and the clinical severity of lesions in SD patients. Although this correlation was statistically significant (P = 0.046), the degree of association (rho = 0.22) was weak. Fifty Malassezia species were identified. M globosa was found in 67% of SD patients, followed by M furfur and M sympodialis, each present in 16.5% of the SD patients. In subjects without skin lesions, the most prevalent species were M globosa (77%), followed by M sympodialis (12%), M slooffiae (7%) and M furfur (4%).The presence of the yeast Malassezia is not associated with the presence of skin lesions.

Highlights

The yeast Malassezia spp has an established etiological role in pityriasis versicolor, folliculitis, systemic infections and onychomycosis
En relación a las especies identificadas (Tabla 3), los hallazgos coinciden en gran parte con los de Makimura[39], quien encontró M furfur en pacientes con dermitis seborreica (DS), pitiriasis versicolor y dermitis atópica; encontró M sympodialis en pacientes con las mis
Al Servicio de Dermatología del Hospital Clínico San Borja-Arriarán, a cada uno de los colegas que compartían sus pacientes para hacer posible este trabajo

Summary

Background

The yeast Malassezia spp has an established etiological role in pityriasis versicolor, folliculitis, systemic infections and onychomycosis. Results: The yeast Malassezia was found in 76% of SD patients and in 82% of subjects without skin lesions. In subjects without skin lesions, the most prevalent species were M globosa (77%), followed by M sympodialis (12%), M slooffiae (7%) and M furfur (4%). En 1889, el término genérico Malassezia fue utilizado por Baillon en honor a Malassez[3,4] para denominar hongos dimórficos observados en lesiones de pitiriasis versicolor e identifica a M furfur como la primera especie de ese género. Molecular logrando identificar 4 nuevas especies de Malassezia: M globosa, M restricta, M obtusa y M slooffiae[7], las que se agregaron a la M sympodialis incorporada en 1990 por Simmons y Guého[8]. El resultado es positivo (+) si se forman burbujas de gas

Crecimiento en Tween

Findings

DS leve DS moderada DS severa Total Control