Caracterización de 130 pacientes sometidos a gastrectomía por cáncer gástrico en el Instituto de Cancerología–Clínica Las Américas de Medellín

Abstract

ObjectiveTo describe the sociodemographic, clinical and histopathology characteristics of patients with gastric cancer and their survival at 1, 3 and 5 years after undergoing gastrectomy in the Instituto de Cancerología (IDC)–Las Américas between 2006 and 2011. MethodsA descriptive, retrospective and prospective study was conducted with patients diagnosed with gastric adenocarcinoma during a period of five years. An analysis was performed using descriptive statistics and the Kaplan-Meier method to estimate survival. ResultsThe study included 130 patients, with a mean age of 62.2 years, and the majority (78.5%) were residents in the Valle de Aburrá. The most common histological finding was the intestinal type (52%), with a high frequency of diffuse type. Helicobacter pylori was found in 30% of patients, 20% of them had a family history of gastric cancer, and 35% were signet ring cells type. Subtotal gastrectomy was performed on 64%, and 47% required adjuvant chemotherapy. Overall survival was 81%, 54%, and 48% at 1, 3 and 5 years, respectively, with longer survival in patients younger than 55 years with diffuse type of cancer. ConclusionsThe results of this study describe the presence of gastric cancer, more often in men, older adults, and mountainous area residents, with associated factors such as first-degree family history and the presence of H. pylori.