Abstract

The objective of this study was to evaluate the clinical and laboratorial aspects of dogs with adrenocorticotropic hormone- (ACTH) dependent hypercortisolism in a series of cases (131). Females predominate (63%); the mean age was 10 years; the most frequent breeds were Shih-tzu (15.27%), Poodle (14.50%) and Yorkshire (14.50%); the most common laboratorial findings were elevation in alanine aminotransferase (ALT) (49.56%) and alkaline phosphatase (ALP) (75.65%) activity, hypercholesterolemia (51.72%) and hypertriglyceridemia (74.34%); the most frequent clinical manifestations were polyuria (47.86%), polydipsia (54.70%) and polyphagia (47.00%), and the most frequent comorbidities were hepatopathies (70.16%), gallbladder diseases (66.13%) and dermatopathies (11.29%). It was concluded that the patients characterization was similar to previous studies, but with a lower frequency of clinical manifestations, suggesting diagnosis was made in the earlier stages.

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