Abstract

BACKGROUND: Captagon, Octodrine, and NBOMe are unique substances; each represents a chemical category of its own pharmacodynamic and pharmacokinetic properties. Captagon is an amphetamine-type stimulant, while octodrine is a sympathomimetic agent, on the other hand, NBOMe is a hallucinogen (psychedelic substance). However, the mechanism of action for each is exerted via monoamine transporters.MATERIALS & METHODS: This study will explore these substances using an integrative approach via the analysis of the surface and deep web, and a trends database. The aims are; to visualise the extent of diffusion of each substance on the internet, conclude the geo-mapping for the diffusion, to see if the patterns are compatible on both divisions of the web, and to infer data on the basis of the power (authority) for e-vendors on the darknet e-marketplace. This study is a hybrid of cross-sectional and retrospective analyses.RESULTS: Google Trends analyses confirmed that the popularity of captagon is ahead over both NBOMe and octodrine; captagon popularity was correlated with terror attacks in the developed world, particularly in western European countries. The contribution of the developing countries to the diffusion of these substances, including the Middle East, was minimal.CONCLUSION: This study proposes a novel method to analyse the e-markets on the darknet via the use of; analysis of the basis of power, inferential statistics, geo-mapping in parallel with data from Google Trends database. Data from Google Trends can serve as a foundation for data mining techniques for an efficient warning system against an anticipated swarm of intoxications or an attack of terror.

Highlights

  • Captagon, Octodrine, and NBOMe are unique substances; each represents a chemical category of its own pharmacodynamic and pharmacokinetic properties

  • Google Trends analyses confirmed that the popularity of captagon is ahead over both NBOMe and octodrine; captagon popularity was correlated with terror attacks in the developed world, in western European countries

  • This study proposes a novel method to analyse the e-markets on the darknet via the use of; analysis of the basis of power, inferential statistics, geo-mapping in parallel with data from Google Trends database

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Summary

Introduction

Octodrine, and NBOMe are unique substances; each represents a chemical category of its own pharmacodynamic and pharmacokinetic properties. Three distinct substances will be explored; Captagon (fenethylline), Octodrine (DMHA), and n-bomb (NBOMe) Each of these substances represents a unique class of its own and having its peculiar pharmacodynamics and pharmacokinetics; captagon is an amphetamine-type stimulant (ATS), octodrine is a sympathomimetic agent, while NBOMe is a hallucinogenic substance (psychedelic) (Ling et al, 2013; Nichols 2016; Rao and Hoffman, 2014). Captagon has been linked to the terror attacks in Western Europe in the past years; it is an amphetamine-type stimulant which can highly potentiate the physical abilities of its users by reducing the need for rest and sleep It has been widely used in conflict zones by militias and terrorist organizations, and in the planning for gjhs.ccsenet.org

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