Abstract
Capsule endoscopy (CE) has proven to be a valuable diagnostic modality for small bowel diseases over the past 20 years, particularly Crohn’s disease (CD), which can affect the entire gastrointestinal tract from the mouth to the anus. CE is not only used for the diagnosis of patients with suspected small bowel CD, but can also be used to assess disease activity, treat-to-target, and postoperative recurrence in patients with established small bowel CD. As CE can detect even mildly non-specific small bowel lesions, a high diagnostic yield is not necessarily indicative of high diagnostic accuracy. Moreover, the cost effectiveness of CE as a third diagnostic test employed usually after ileocolonoscopy and MR or CT enterography is an important consideration. Recently, new developments in colon capsule endoscopy (CCE) have increased the utility of CE in patients with ulcerative colitis (UC) and pan-enteric CD. Although deflation of the colon during the examination and the inability to evaluate dysplasia-associated lesion or mass results in an inherent risk of overestimation or underestimation, the convenience of CCE examination and the risk of flare-up after colonoscopy suggest that CCE could be used more actively in patients with UC.
Highlights
Retention in patients with established CD (ECD) [22]. These results suggest that cross-sectional imaging of the small bowel should be performed prior to Capsule endoscopy (CE) to determine the presence of strictures in patients with Crohn’s disease (CD)
CE is being developed in several ways, including the development of CE instruments with higher frame rates and increased image resolution, which should increase the possibility of obtaining higher diagnostic yield and accuracy than in the past [35]
This method increased diagnostic yield by 24% in patients with perianal disease and negative conventional work up, including ileocolonoscopy [47]. These results showed that CE is a useful test for the diagnosis of CD in patients who have not been diagnosed by conventional modalities, such as gastroscopy, ileocolonoscopy, and small bowel follow-through (SBFT)
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. As CE allows direct observation of the small intestine, it is able to visualize even mildly inflammatory mucosal lesions, such as erythema, erosion, and small ulcers, which are difficult to detect with radiological imaging modalities such as small bowel follow-through (SBFT), small bowel contrast ultrasound (SBCUS), CT enterography (CTE), and MR enterography (MRE) [3]. This advantage has aided in precision medicine-based diagnostic and therapeutic decision-making, especially in patients with suspected or established Crohn’s disease (CD) of the small intestine. This review will describe the clinical applications and value of CE in the diagnosis and management of inflammatory bowel disease
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
