Abstract
Capsaicin, the pungency-impat1ing alkaloid, is found only in the Capsicum genus. Capsaicin biosynthesis involves the phenyl propanoid and valine pathways and a final condensation step to involve ~'anillylamjne and 8-methyl nonenok acid catalysed by capsaicin synthase. In recent times, capsaicin has been one of the most highly exploited biomolecules because of its versatility in application. So far, researchers have reported capsaicin as an antioxidant. antiarthritic. gastroprotcctive agent, anticancer (also procancer) agent and an analgesic. This review is a compilation of reports on the biosynthesis of capsaicin in Capsicum spp .. the exploitation of capsaicin in pharmacy and the molecular mechanisms involved in capsaicin receptors.
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