Abstract
The capillary bed of the brain, consisting of endothelial cells and pericytes, regulates local blood flow and facilitates the delivery of oxygen and nutrients to meet neuronal energy requirements over rapid timescales. Despite increasing experimental scrutiny, the physiological contributions of pericytes to brain blood flow control remain elusive. ATP-sensitive potassium (KATP) channels, composed of Kir6.1 and SUR2 subunits, are the most robustly expressed ion channels in pericytes, with little or no expression of these subunits in arteriolar smooth muscle cells and capillary or arteriolar endothelial cells.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
