Abstract
(Current Biology 31, 3639–3647.e1–e5; August 23, 2021) Since publication, errors have been identified in Figure 1H and the text referring to it. The x axis in Figure 1H was mistakenly labeled with the numbers “250 260 260 260.” These labels have been corrected to “230 240 250 260.” The corrected numbering accurately reflects the range of concentration values used in the calculated search times based on the Smoluchowski equation. In the sentence of the text referring to Figure 1H, the range of plausible concentration values used to generate the plot has been corrected to 225–262 nM. These corrections do not change our interpretation of the search times. Additionally, the parenthetical phrase in the sentence after the reference to Figure 1H in the text contains a spelling error. “C = 290 nm” has been changed to “C = 290 nM” to accurately represent the unit of concentration as nanomolar. The authors apologize for these errors and any confusion they may have caused.Figure 1HMeasurements of Cic concentration and mobility in interphase nuclei (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Capicua is a fast-acting transcriptional brakePatel et al.Current BiologyJune 23, 2021In BriefPatel et al. report the timescale of transcriptional repression by Capicua in the early Drosophila embryo. Biophysical properties of Capicua are measured in interphase nuclei. Optimized photoswitchable MEK toggles gene repression. Optogenetic perturbations and live reporters of nascent transcript production reveal fast-acting gene repression. Full-Text PDF Open Archive
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