Abstract
Capecitabine is an oral prodrug to 5-fluorouracil and is commonly used in the treatment of advanced breast, colon and stomach cancer. While gastrointestinal toxicity is common, enterocolitis and ischemic colitis are uncommon complications and the histologic features of capecitabine in the colonic mucosa have not been previously described. We present a case of colitis attributed to capecitabine toxicity in a 45-year-old man undergoing treatment of metastatic gastroesophageal adenocarcinoma. Possible pathophysiologic mechanisms of capecitabine toxicity are discussed and the histologic effects on the colon are described.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
