Abstract
Capacitive biosensors belong to the group of affinity biosensors that operate by registering direct binding between the sensor surface and the target molecule. This type of biosensors measures the changes in dielectric properties and/or thickness of the dielectric layer at the electrolyte/electrode interface. Capacitive biosensors have so far been successfully used for detection of proteins, nucleotides, heavy metals, saccharides, small organic molecules and microbial cells. In recent years, the microcontact imprinting method has been used to create very sensitive and selective biorecognition cavities on surfaces of capacitive electrodes. This chapter summarizes the principle and different applications of capacitive biosensors with an emphasis on microcontact imprinting method with its recent capacitive biosensor applications.
Highlights
Affinity biosensors can be divided into two main groups: those that measure direct binding between the target molecule and the affinity surface on the sensor, and those biosensors which are adopted to binding assays using labelled reagents [1]
This review deals with capacitive biosensors, different applications of capacitive biosensors developed for both detection of various targets and by using molecular imprinting technology with an emphasis on microcontact imprinting method
Labib et al [9] developed a sensitive method for detection of cholera toxin (CT) using a flow-injection capacitive immunosensor based on self-assembled monolayers
Summary
Affinity biosensors can be divided into two main groups: those that measure direct binding between the target molecule and the affinity surface on the sensor, and those biosensors which are adopted to binding assays using labelled reagents [1]. Among the different types of label-free biosensors, electrochemical biosensors have received particular attention owing to their properties [4] These biosensors can be miniaturized which is very important for many applications that need portable integrated systems. Miniaturization allows use at point of care, in a clinic, doctor’s office or at home and reduces the cost of the diagnostic assays Electrical biosensors fulfil these purposes as being fast, cheap, portable, miniaturized and label-free devices. This review deals with capacitive biosensors, different applications of capacitive biosensors developed for both detection of various targets and by using molecular imprinting technology with an emphasis on microcontact imprinting method In this aspect, this is a novel review which includes the two technologies, capacitive biosensors and molecular imprinting; at the same time with lots of examples from published reports. The reports in molecular imprinting section were selected mainly from capacitive biosensors developed by using microcontact imprinting method
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
