Cannabinoids as dental pulp capping agents: a scoping review protocol

Abstract

Exposure of the dental pulp and its contamination with bacteria from the oral environment can lead to pulp inflammation, toothache, necrosis and, in immature teeth, interruption of the rhizogenesis process; Therefore, it makes sense to suggest that bioactive materials can lead to the maintenance of pulp viability. Cannabinoids have been investigated in different areas of health and have already been studied in relation to their influence on dental pulp cells and apical papilla stem cells. This work proposes a protocol for the development of a scoping review with the objective of mapping the available literature on the use of cannabinoids as pulp protection agents. This scoping review protocol was prepared following the Peters methodology and the recommendations of the reviewer's manual for scoping reviews of the Joanna Briggs Institute (JBI) and PRISMA-ScR, and was registered in the Open Science Framework (OSF) under the DOI: https://doi.org/10.17605/OSF.IO/HYD28. Searches will be carried out in the Pubmed, Web of Science, Scopus, Cochrane, LILACS and VHL Portal databases, as well as in gray literature repositories. Data analysis will be descriptive and will involve both qualitative and quantitative data, from which a narrative synthesis will be constructed on the use of cannabinoids as protective agents for dental pulp. It is expected that the results obtained in this scoping review will provide support for future debates related to the topic and so that knowledge gaps found during the development of the review can be emphasized.