Abstract
ABSTRACT:Vaccines used routinely for canine vaccination include modified live vaccines (MLVs) and killed vaccines. MLVs have higher immunogenicity than killed vaccines meaning that they are more successful at eliciting an immune response. Studies into the duration of immunity (DOI) of MLVs have helped introduce the extended revaccination interval of three years and many vaccine manufacturers have now relicensed their products for such use. Although suspected adverse reactions (SARs) to vaccination are rare, extended revaccination intervals should help reduce the number seen in practice. It is important to be aware of the possible reactions and to ensure these are reported appropriately. Vaccine failure is rare but may arise owing to poor response on the part of the individual, the presence of maternally derived antibodies (MDA) and environmental factors, such as inappropriate vaccine storage. The Vaccination Guidelines Group (VGG) recommendations cover the issue of maternally derived antibodies (MDA), extended revaccination intervals and the use of serology to determine whether a booster is needed.
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